This session will explore a new type of nature-based solutions for vector-borne diseases control using a naturally occurring phenomenon called gene drive. Vector-borne diseases have a heavy burden on both public health (with over 700,000 deaths/year according to WHO) and biodiversity with numerous species threatened (e.g. Hawaiian birds threatened by avian malaria). The current methods for vector control are largely relying on insecticides. This has proved efficacious in the past and has allowed to saving millions of lives, but with growing insecticide-resistance and concerns about the scalability, there is a consensus that additional tools are required to reach the SDGs. Gene drive research can be a new avenue to explore at the crossroad of public health and biodiversity considerations.